Slaying RAS with a synthetic lethal weapon
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/cr201016.pdf
Reference15 articles.
1. Kaelin WG, Jr Synthetic lethality: a framework for the development of wiser cancer therapeutics. Genome Med 2009; 1:99.
2. Hartwell LH, Szankasi P, Roberts CJ, Murray AW, Friend SH . Integrating genetic approaches into the discovery of anticancer drugs. Science 1997; 278:1064–1068.
3. Kaelin WG, Jr The concept of synthetic lethality in the context of anticancer therapy. Nat Rev Cancer 2005; 5:689–698.
4. Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T . Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411:494–498.
5. Luo J, Emanuele MJ, Li D, et al. A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Cell 2009; 137:835–848.
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