A screen of Crohn’s disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells-Reference-Cited by-同舟云学术

A screen of Crohn’s disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells

Published:2018-04-25 Issue:2 Volume:12 Page:457-467
ISSN:1933-0219
Container-title:Mucosal Immunology
language:en
Short-container-title:Mucosal Immunol

Author:

Chang Yu-Ling,Rossetti Maura,Vlamakis Hera,Casero David,Sunga Gemalene,Harre Nicholas,Miller Shelley,Humphries Romney,Stappenbeck Thaddeus,Simpson Kenneth W.,Sartor R. Balfour,Wu Gary,Lewis James,Bushman Frederic,McGovern Dermot P. B.,Salzman Nita,Borneman James,Xavier Ramnik,Huttenhower Curtis,Braun Jonathan

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/s41385-018-0022-7.pdf

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3. Sartor, R. B. & Wu, G. D. Roles for intestinal bacteria, viruses, and fungi in pathogenesis of inflammatory bowel diseases and therapeutic approaches. Gastroenterology 152, 327–339.e324 (2017).

4. Brestoff, J. R. & Artis, D. Commensal bacteria at the interface of host metabolism and the immune system. Nat. Immunol. 14, 676–684 (2013).

5. Dorrestein, P. C., Mazmanian, S. K. & Knight, R. Finding the missing links among metabolites, microbes, and the host. Immunity 40, 824–832 (2014).

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