A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4+ T cells and is defective in Crohn´s disease patients

Author:

Ahlers Jonas,Mantei Andrej,Lozza Laura,Stäber Manuela,Heinrich Frederik,Bacher Petra,Hohnstein Thordis,Menzel Lutz,Yüz Simge G.,Alvarez-Simon Daniel,Bickenbach Anne Rieke,Weidinger Carl,Mockel-Tenbrinck Nadine,Kühl Anja A.,Siegmund Britta,Maul Jochen,Neumann Christian,Scheffold AlexanderORCID

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference78 articles.

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2. Functions and regulation of T cell-derived interleukin-10;Neumann;Semin Immunol.,2019

3. IL-10 in humans: lessons from the gut, IL-10/IL-10 receptor deficiencies, and IL-10 polymorphisms;Engelhardt;Curr. Top. Microbiol Immunol.,2014

4. Interleukin-10-deficient mice develop chronic enterocolitis;Kuhn;Cell,1993

5. Regulation and functions of the IL-10 family of cytokines in inflammation and disease;Ouyang;Annu. Rev. Immunol.,2011

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