Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity-Reference-Cited by-同舟云学术

Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity

Published:2005-02-20 Issue:3 Volume:23 Page:344-348
ISSN:1087-0156
Container-title:Nature Biotechnology
language:en
Short-container-title:Nat Biotechnol

Author:

Hoet René Michael,Cohen Edward H,Kent Rachel Baribault,Rookey Kristin,Schoonbroodt Sonia,Hogan Shannon,Rem Louise,Frans Nicolas,Daukandt Marc,Pieters Henk,van Hegelsom Rob,Neer Nicole Coolen-van,Nastri Horacio G,Rondon Isaac J,Leeds Jennifer A,Hufton Simon E,Huang Lili,Kashin Irina,Devlin Mary,Kuang Guannan,Steukers Mieke,Viswanathan Malini,Nixon Andrew E,Sexton Daniel J,Hoogenboom Hennie R,Ladner Robert Charles

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

http://www.nature.com/articles/nbt1067.pdf

Reference30 articles.

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3. Cardarelli, P.M. et al. Binding to CD20 by anti-B1 antibody or F(ab')(2) is sufficient for induction of apoptosis in B-cell lines. Cancer Immunol. Immunother. 51, 15–24 (2002).

4. Santora, L.C., Kaymakcalan, Z., Sakorafas, P., Krull, I.S. & Grant, K. Characterization of noncovalent complexes of recombinant human monoclonal antibody and antigen using cation exchange, size exclusion chromatography, and BIAcore. Anal. Biochem. 299, 119–129 (2001).

5. Knight, D.M. et al. Construction and initial characterization of a mouse-human chimeric anti-TNF antibody. Mol. Immunol. 30, 1443–1453 (1993).

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