Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes-Reference-Cited by-同舟云学术

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes

Published:2013-10-20 Issue:11 Volume:19 Page:1496-1504
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Hasegawa Kazuhiro,Wakino Shu,Simic Petra,Sakamaki Yusuke,Minakuchi Hitoshi,Fujimura Keiko,Hosoya Kozi,Komatsu Motoaki,Kaneko Yuka,Kanda Takeshi,Kubota Eiji,Tokuyama Hirobumi,Hayashi Koichi,Guarente Leonard,Itoh Hiroshi

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.3363.pdf

Reference53 articles.

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3. Bordone, L. & Guarente, L. Calorie restriction, SIRT1 and metabolism: understanding longevity. Nat. Rev. Mol. Cell Biol. 6, 298–305 (2005).

4. Purushotham, A. et al. Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Cell Metab. 9, 327–338 (2009).

5. Wang, R.H. et al. Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance. J. Clin. Invest. 121, 4477–4490 (2011).

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