Discovery and development of the Polo-like kinase inhibitor volasertib in cancer therapy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
http://www.nature.com/articles/leu2014222.pdf
Reference75 articles.
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3. Liu X, Erikson RL . Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells. Proc Natl Acad Sci USA 2003; 100: 5789–5794.
4. Tamura Y, Simizu S, Muroi M, Takagi S, Kawatani M, Watanabe N et al. Polo-like kinase 1 phosphorylates and regulates Bcl-x(L) during pironetin-induced apoptosis. Oncogene 2009; 28: 107–116.
5. Rizki A, Mott JD, Bissell MJ . Polo-like kinase 1 is involved in invasion through extracellular matrix. Cancer Res 2007; 67: 11106–11110.
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