Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection-Reference-Cited by-同舟云学术

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Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection

Published:2022-09-29 Issue:3 Volume:19 Page:275-283
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Oh Chang-ki^ORCID,Nakamura Tomohiro,Beutler Nathan,Zhang Xu,Piña-Crespo Juan,Talantova Maria,Ghatak Swagata,Trudler Dorit,Carnevale Lauren N.^ORCID,McKercher Scott R.,Bakowski Malina A.,Diedrich Jolene K.,Roberts Amanda J.,Woods Ashley K.,Chi Victor,Gupta Anil K.,Rosenfeld Mia A.^ORCID,Kearns Fiona L.,Casalino Lorenzo^ORCID,Shaabani Namir,Liu Hejun^ORCID,Wilson Ian A.^ORCID,Amaro Rommie E.^ORCID,Burton Dennis R.^ORCID,Yates John R.^ORCID,Becker Cyrus^ORCID,Rogers Thomas F.,Chatterjee Arnab K.^ORCID,Lipton Stuart A.^ORCID

Funder

Foundation for the National Institutes of Health

California Institute for Regenerative Medicine

COVID-19 awards from Fast Grants

Bill and Melinda Gates Foundation

National Science Foundation

the RCSA Research Corp. and a UC San Diego Moore’s Cancer Center 2020 SARS-CoV-2 seed grant

Bill and Melinda Gates Institute for Population and Reproductive Health

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

https://www.nature.com/articles/s41589-022-01149-6.pdf

Reference60 articles.

1. Hoffmann, M. et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell 181, 271–280 (2020).

2. Kozakov, D., Chuang, G. Y., Beglov, D. & Vajda, S. Where does amantadine bind to the influenza virus M2 proton channel? Trends Biochem. Sci. 35, 471–475 (2010).

3. Torres, J. et al. Conductance and amantadine binding of a pore formed by a lysine-flanked transmembrane domain of SARS coronavirus envelope protein. Protein Sci. 16, 2065–2071 (2007).

4. Asarnow, D. et al. Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia. Cell 184, 3192–3204 (2021).

5. Lipton, S. A. Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond. Nat. Rev. Drug Discov. 5, 160–170 (2006).

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