Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders-Reference-Cited by-同舟云学术

Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

Published:2022-11-03 Issue:3 Volume:19 Page:323-333
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Hanzl Alexander^ORCID,Casement Ryan^ORCID,Imrichova Hana^ORCID,Hughes Scott J.,Barone Eleonora,Testa Andrea,Bauer Sophie,Wright Jane,Brand Matthias,Ciulli Alessio^ORCID,Winter Georg E.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

https://www.nature.com/articles/s41589-022-01177-2.pdf

Reference60 articles.

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3. Hanzl, A. & Winter, G. E. Targeted protein degradation: current and future challenges. Curr. Opin. Chem. Biol. 56, 35–41 (2020).

4. Petroski, M. D. & Deshaies, R. J. Function and regulation of cullin-RING ubiquitin ligases. Nat. Rev. Mol. Cell Biol. 6, 9–20 (2005).

5. Harper, J. W. & Schulman, B. A. Cullin-RING ubiquitin ligase regulatory circuits: a quarter century beyond the F-box hypothesis. Annu. Rev. Biochem. 90, 403–429 (2021).

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