Direct inhibition of tumor hypoxia response with synthetic transcriptional repressors
Author:
Funder
U.S. Department of Health & Human Services | National Institutes of Health
American Cancer Society
U.S. Department of Defense
V Foundation for Cancer Research
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41589-024-01716-z.pdf
Reference66 articles.
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3. Kim, J. W., Gao, P. & Dang, C. V. Effects of hypoxia on tumor metabolism. Cancer Metastasis Rev. 26, 291–298 (2007).
4. Liao, D. & Johnson, R. S. Hypoxia: a key regulator of angiogenesis in cancer. Cancer Metastasis Rev. 26, 281–290 (2007).
5. Lee, A. H., Iwakoshi, N. N. & Glimcher, L. H. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol. Cell. Biol. 23, 7448–7459 (2003).
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