Circularly permuted LOV2 as a modular photoswitch for optogenetic engineering
Author:
Funder
American Cancer Society
Welch Foundation
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/s41589-021-00792-9.pdf
Reference42 articles.
1. Tischer, D. & Weiner, O. D. Illuminating cell signalling with optogenetic tools. Nat. Rev. Mol. Cell Biol. 15, 551–558 (2014).
2. Losi, A., Gardner, K. H. & Moglich, A. Blue-light receptors for optogenetics. Chem. Rev. 118, 10659–10709 (2018).
3. Harper, S. M., Neil, L. C. & Gardner, K. H. Structural basis of a phototropin light switch. Science 301, 1541–1544 (2003).
4. Baird, G. S., Zacharias, D. A. & Tsien, R. Y. Circular permutation and receptor insertion within green fluorescent proteins. Proc. Natl Acad. Sci. USA 96, 11241–11246 (1999).
5. Yu, Y. & Lutz, S. Circular permutation: a different way to engineer enzyme structure and function. Trends Biotechnol. 29, 18–25 (2011).
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