Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus-Reference-Cited by-同舟云学术

Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus

Published:2022-03-31 Issue:7 Volume:18 Page:706-712
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Brawley Douglas N.,Sauer David B.,Li Jianping,Zheng Xuhui,Koide Akiko,Jedhe Ganesh S.^ORCID,Suwatthee Tiffany,Song Jinmei,Liu Zheng^ORCID,Arora Paramjit S.,Koide Shohei^ORCID,Torres Victor J.^ORCID,Wang Da-Neng^ORCID,Traaseth Nathaniel J.^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences

American Cancer Society

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke

U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

NSF | BIO | Division of Molecular and Cellular Biosciences

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

https://www.nature.com/articles/s41589-022-00994-9.pdf

Reference59 articles.

1. Antibiotic Resistance Threats in the United States, 2019 (Centers for Disease Control and Prevention, 2019); https://doi.org/10.15620/cdc:82532

2. Nikaido, H. Multidrug resistance in bacteria. Annu. Rev. Biochem. 78, 119–146 (2009).

3. Du, D. et al. Multidrug efflux pumps: structure, function and regulation. Nat. Rev. Microbiol. 16, 523–539 (2018).

4. Piddock, L. J. Multidrug-resistance efflux pumps—not just for resistance. Nat. Rev. Microbiol. 4, 629–636 (2006).

5. Singh, R. et al. Temporal interplay between efflux pumps and target mutations in development of antibiotic resistance in Escherichia coli. Antimicrob. Agents Chemother. 56, 1680–1685 (2012).

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