Discovery of a ZIP7 inhibitor from a Notch pathway screen
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Published:2019-01-14
Issue:2
Volume:15
Page:179-188
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ISSN:1552-4450
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Container-title:Nature Chemical Biology
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language:en
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Short-container-title:Nat Chem Biol
Author:
Nolin Erin, Gans Sara, Llamas Luis, Bandyopadhyay Somnath, Brittain Scott M., Bernasconi-Elias Paula, Carter Kyle P., Loureiro Joseph J., Thomas Jason R., Schirle Markus, Yang Yi, Guo Ning, Roma GuglielmoORCID, Schuierer Sven, Beibel Martin, Lindeman Alicia, Sigoillot FredericORCID, Chen Amy, Xie Kevin X., Ho Samuel, Reece-Hoyes John, Weihofen Wilhelm A., Tyskiewicz Kayla, Hoepfner DominicORCID, McDonald Richard I., Guthrie Nicolette, Dogra Abhishek, Guo Haibing, Shao Jian, Ding Jian, Canham Stephen M., Boynton Geoff, George Elizabeth L., Kang Zhao B., Antczak Christophe, Porter Jeffery A., Wallace Owen, Tallarico John A., Palmer Amy E.ORCID, Jenkins Jeremy L.ORCID, Jain Rishi K., Bushell Simon M.ORCID, Fryer Christy J.ORCID
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Reference61 articles.
1. Imming, P., Sinning, C. & Meyer, A. Drugs, their targets and the nature and number of drug targets. Nat. Rev. Drug Discov. 5, 821–834 (2006). 2. Overington, J. P., Al-Lazikani, B. & Hopkins, A. L. How many drug targets are there? Nat. Rev. Drug Discov. 5, 993–996 (2006). 3. Whitfield, J. R., Beaulieu, M. E. & Soucek, L. Strategies to inhibit Myc and their clinical applicability. Front. Cell Dev. Biol. 5, 10 (2017). 4. Hori, K., Sen, A. & Artavanis-Tsakonas, S. Notch signaling at a glance. J. Cell Sci. 126, 2135–2140 (2013). 5. Weng, A. P. et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306, 269–271 (2004).
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