Enzymology of assembly line synthesis by modular polyketide synthases
Author:
Funder
Hessisches Ministerium für Wissenschaft und Kunst
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
https://www.nature.com/articles/s41589-023-01277-7.pdf
Reference98 articles.
1. Cortes, J., Haydock, S. F., Roberts, G. A., Bevitt, D. J. & Leadlay, P. F. An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea. Nature 348, 176–178 (1990).
2. Staunton, J. & Weissman, K. J. Polyketide biosynthesis: a millennium review. Nat. Prod. Rep. 18, 380–416 (2001).
3. Hertweck, C. The biosynthetic logic of polyketide diversity. Angew. Chem. Int. Ed. 48, 4688–4716 (2009).
4. Weissman, K. J. The structural biology of biosynthetic megaenzymes. Nat. Chem. Biol. 11, 660–670 (2015).
5. Staunton, J. & Wilkinson, B. Biosynthesis of erythromycin and rapamycin. Chem. Rev. 97, 2611–2630 (1997).
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