Phosphatidylinositol-3-phosphate is light-regulated and essential for survival in retinal rods
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep26978.pdf
Reference37 articles.
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2. Ivanovic, I. et al. Deletion of the p85α regulatory subunit of phosphoinositide 3-kinase in cone photoreceptor cells results in cone photoreceptor degeneration. Invest. Ophthalmol. Vis. Sci. 52, 3775–3783 (2011).
3. Chuang, J. Z., Zhao, Y. & Sung, C. H. SARA-regulated vesicular targeting underlies formation of the light-sensing organelle in mammalian rods. Cell 130, 535–547 (2007).
4. Li, H. & Marshall, A. J. Phosphatidylinositol (3,4) bisphosphate-specific phosphatases and effector proteins: A distinct branch of PI3K signaling. Cell Signal. 27, 1789–1798 (2015).
5. Campa, C. C., Franco, I. & Hirsch, E. PI3K-C2α: One enzyme for two products coupling vesicle trafficking and signal transduction. FEBS Lett. 589, 1552–1558 (2015).
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