Rescue of a deficiency in ATP synthesis by transfer of MTATP6, a mitochondrial DNA-encoded gene, to the nucleus

Author:

Manfredi Giovanni,Fu Jin,Ojaimi Joseline,Sadlock James E.,Kwong Jennifer Q.,Guy John,Schon Eric A.

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Reference44 articles.

1. Holt, I.J., Harding, A.E., Petty, R.K.H. & Morgan-Hughes, J.A. A new mitochondrial disease associated with mitochondrial DNA heteroplasmy. Am. J. Hum. Genet. 46, 428–433 (1990).

2. Tatuch, Y. et al. Heteroplasmic mtDNA mutation (T→G) at 8993 can cause Leigh's disease when the percentage of abnormal mtDNA is high. Am. J. Hum. Genet. 50, 852–858 (1992).

3. Law, R.H., Farrell, L.B., Nero, D., Devenish, R.J. & Nagley, P. Studies on the import into mitochondria of yeast ATP synthase subunits 8 and 9 encoded by artificial nuclear genes. FEBS Lett. 236, 501–505 (1988).

4. DiMauro, S. & Andreu, A.L. Mutations in mtDNA: are we scraping the bottom of the barrel? Brain Pathol. 10, 431–441 (2000).

5. Anderson, S. et al. Sequence and organization of the human mitochondrial genome. Nature 290, 457–465 (1981).

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