A unifying mathematical framework for experimental TCR-pMHC kinetic constants
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep46741.pdf
Reference30 articles.
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2. Rosette, C. et al. The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model. Immunity 15, 59–70, doi: 10.1016/S1074-7613(01)00173-X (2001).
3. Holler, P. D., Lim, A. R., Cho, B. K., Rund, L. A. & Kranz, D. M. CD8-T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation. The Journal of experimental medicine 194, 1043–1052, doi: 10.1084/jem.194.8.1043 (2001).
4. Holler, P. D., Chlewicki, L. K. & Kranz, D. M. TCRs with high affinity for foreign pMHC show self-reactivity. Nature immunology 4, 55–62, doi: 10.1038/ni863 (2003).
5. Gakamsky, D. M., Luescher, I. F. & Pecht, I. T cell receptor-ligand interactions: a conformational preequilibrium or an induced fit. Proceedings of the National Academy of Sciences of the United States of America 101, 9063–9066, doi: 10.1073/pnas.0402840101 (2004).
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