Synapse-tuned CARs enhance immune cell anti-tumor activity-Reference-Cited by-同舟云学术

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Synapse-tuned CARs enhance immune cell anti-tumor activity

Published:2023-02-02 Issue:10 Volume:41 Page:1434-1445
ISSN:1087-0156
Container-title:Nature Biotechnology
language:en
Short-container-title:Nat Biotechnol

Author:

Chockley Peter J.^ORCID,Ibanez-Vega Jorge^ORCID,Krenciute Giedre^ORCID,Talbot Lindsay J.,Gottschalk Stephen^ORCID

Funder

Center for Strategic Scientific Initiatives, National Cancer Institute

St Jude Sumara Fellowship

The Garwood Postdoctoral Fellowship

ChadTough Foundation

U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke

Rally Foundation

American Lebanese Syrian Associated Charities

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://www.nature.com/articles/s41587-022-01650-2.pdf

Reference55 articles.

1. Maude, S. L. et al. Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia. N. Engl. J. Med. 378, 439–448 (2018).

2. Schuster, S. J. et al. Chimeric antigen receptor T cells in refractory B-cell lymphomas. N. Engl. J. Med. 377, 2545–2554 (2017).

3. Kingwell, K. CAR T therapies drive into new terrain. Nat. Rev. Drug Discov. 16, 301–304 (2017).

4. Chiossone, L., Dumas, P. Y., Vienne, M. & Vivier, E. Natural killer cells and other innate lymphoid cells in cancer. Nat. Rev. Immunol. 18, 671–688 (2018).

5. Davenport, A. J. et al. Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity. Proc. Natl Acad. Sci. USA 115, E2068–E2076 (2018).

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