Self-organizing neuruloids model developmental aspects of Huntington’s disease in the ectodermal compartment
Author:
Publisher
Springer Science and Business Media LLC
Subject
Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
http://www.nature.com/articles/s41587-019-0237-5.pdf
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3. Ozair, M. Z., Noggle, S., Warmflash, A., Krzyspiak, J. E. & Brivanlou, A. H. SMAD7 directly converts human embryonic stem cells to telencephalic fate by a default mechanism. Stem Cells 31, 35–47 (2013).
4. Dincer, Z. et al. Specification of functional cranial placode derivatives from human pluripotent stem cells. Cell Rep. 5, 1387–1402 (2013).
5. Tchieu, J. et al. A modular platform for differentiation of human PSCs into all major ectodermal lineages. Cell Stem Cell 21, 399–410 e397 (2017).
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