Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate-Reference-Cited by-同舟云学术

Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate

Published:2017-01-06 Issue:1 Volume:7 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Moniz Larissa S.,Surinova Silvia,Ghazaly Essam,Velasco Lorena Gonzalez,Haider Syed,Rodríguez-Prados Juan Carlos,Berenjeno Inma M.,Chelala Claude,Vanhaesebroeck Bart

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep39985.pdf

Reference65 articles.

1. Okkenhaug, K., Graupera, M. & Vanhaesebroeck, B. Targeting PI3K in Cancer: Impact on Tumor Cells, Their Protective Stroma, Angiogenesis, and Immunotherapy. Cancer Discov 6, 1090–1105 (2016).

2. Vanhaesebroeck, B., Whitehead, M. A. & Pineiro, R. Molecules in medicine mini-review: isoforms of PI3K in biology and disease. J Mol Med (Berl) 94, 5–11 (2016).

3. Engelman, J. A. Targeting PI3K signalling in cancer: opportunities, challenges and limitations. Nat Rev Cancer 9, 550–562 (2009).

4. Samuels, Y. et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 304, 554 (2004).

5. Li, J. et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275, 1943–1947 (1997).

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration;Molecular Oncology;2024-02-20

2. Species- and strain-specific differences in the phagocytosis of Prototheca : insights from live-cell imaging;Infection and Immunity;2023-09-14

3. Genetic Heterogeneity and Tissue-specific Patterns of Tumors with MultiplePIK3CAMutations;Clinical Cancer Research;2023-01-03

4. At a crossroads: how to translate the roles of PI3K in oncogenic and metabolic signalling into improvements in cancer therapy;Nature Reviews Clinical Oncology;2022-04-28

5. Platelet transcriptome identifies progressive markers and potential therapeutic targets in chronic myeloproliferative neoplasms;Cell Reports Medicine;2021-10