Phase I/II trial of a dendritic cell vaccine transfected with DNA encoding melan A and gp100 for patients with metastatic melanoma-Reference-Cited by-同舟云学术

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Phase I/II trial of a dendritic cell vaccine transfected with DNA encoding melan A and gp100 for patients with metastatic melanoma

Published:2011-02-10 Issue:6 Volume:18 Page:584-593
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Steele J C,Rao A,Marsden J R,Armstrong C J,Berhane S,Billingham L J,Graham N,Roberts C,Ryan G,Uppal H,Walker C,Young L S,Steven N M

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/gt20111.pdf

Reference48 articles.

1. Ueno H, Klechevsky E, Morita R, Aspord C, Cao T, Matsui T et al. Dendritic cell subsets in health and disease. Immunol Rev 2007; 219: 118–142.

2. Gilboa E . DC-based cancer vaccines. J Clin Invest 2007; 117: 1195–1203.

3. Luo D, Saltzman WM . Synthetic DNA delivery systems. Nat Biotechnol 2000; 18: 33–37.

4. Van Tendeloo VF, Ponsaerts P, Lardon F, Nijs G, Lenjou M, Van Broeckhoven C et al. Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells. Blood 2001; 98: 49–56.

5. Kyte JA, Mu L, Aamdal S, Kvalheim G, Dueland S, Hauser M et al. Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA. Cancer Gene Ther 2006; 13: 905–918.

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