Using non-coding small RNAs to develop therapies for Huntington's disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/gt2011170.pdf
Reference86 articles.
1. The Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993; 72: 971–983.
2. Harper SQ . Progress and challenges in RNA interference therapy for Huntington disease. Arch Neurol 2009; 66: 933–938.
3. Denovan-Wright EM, Davidson BL . RNAi: a potential therapy for the dominantly inherited nucleotide repeat diseases. Gene Therapy 2006; 13: 525–531.
4. Boudreau RL, Davidson BL . RNAi therapy for neurodegenerative diseases. Curr Top Dev Biol 2006; 75: 73–92.
5. Wang YL, Liu W, Wada E, Murata M, Wada K, Kanazawa I . Clinico-pathological rescue of a model mouse of Huntington's disease by siRNA. Neurosci Res 2005; 53: 241–249.
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