Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains-Reference-Cited by-同舟云学术

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Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains

Published:2011-07-14 Issue:4 Volume:19 Page:365-374
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Aggen D H,Chervin A S,Schmitt T M,Engels B,Stone J D,Richman S A,Piepenbrink K H,Baker B M,Greenberg P D,Schreiber H,Kranz D M

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/gt2011104.pdf

Reference80 articles.

1. Bendle GM, Haanen JB, Schumacher TN . Preclinical development of T cell receptor gene therapy. Curr Opin Immunol 2009; 21: 209–214.

2. Morgan RA, Dudley ME, Wunderlich JR, Hughes MS, Yang JC, Sherry RM et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 2006; 314: 126–129.

3. Johnson LA, Morgan RA, Dudley ME, Cassard L, Yang JC, Hughes MS et al. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen. Blood 2009; 114: 535–546.

4. Bendle GM, Linnemann C, Hooijkaas AI, Bies L, de Witte MA, Jorritsma A et al. Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy. Nat Med 2010; 16: 565–570, 561p following 570.

5. Davis MM, Boniface JJ, Reich Z, Lyons D, Hampl J, Arden B et al. Ligand recognition by alpha beta T cell receptors. Annu Rev Immunol 1998; 16: 523–544.

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