Potent, tumor-specific gene expression in an orthotopic hepatoma rat model using a Survivin-targeted, amplifiable adenoviral vector-Reference-Cited by-同舟云学术

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Potent, tumor-specific gene expression in an orthotopic hepatoma rat model using a Survivin-targeted, amplifiable adenoviral vector

Published:2011-02-10 Issue:6 Volume:18 Page:606-612
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Ahn B-C,Ronald J A,Kim Y I,Katzenberg R,Singh A,Paulmurugan R,Ray S,Hofmann L V,Gambhir S S

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/gt20115.pdf

Reference41 articles.

1. Akiyama M, Thorne S, Kirn D, Roelvink PW, Einfeld DA, King CR et al. Ablating CAR and integrin binding in adenovirus vectors reduces nontarget organ transduction and permits sustained bloodstream persistence following intraperitoneal administration. Mol Ther 2004; 9: 218–230.

2. Lo H-W, Day C-P, Hung M-C . Cancer-specific gene therapy. Adv Genet 2005; 54: 235–255.

3. Iyer M, Wu L, Carey M, Wang Y, Smallwood A, Gambhir SS . Two-step transcriptional amplification as a method for imaging reporter gene expression using weak promoters. Proc Natl Acad Sci USA 2001; 98: 14595–14600.

4. Zhang L, Adams JY, Billick E, Ilagan R, Iyer M, Le K et al. Molecular engineering of a two-step transcription amplification (TSTA) system for transgene delivery in prostate cancer. Mol Ther 2002; 5: 223–232.

5. Ray S, Paulmurugan R, Patel MR, Ahn BC, Wu L, Carey M et al. Noninvasive imaging of therapeutic gene expression using a bidirectional transcriptional amplification strategy. Mol Ther 2008; 16: 1848–1856.

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