Concurrent chemotherapy inhibits herpes simplex virus-1 replication and oncolysis

Author:

Kulu Y,Kawasaki H,Donahue J M,Kasuya H,Cusack J C,Choi E W,Kuruppu D K,Fuchs B C,Tanabe K K

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology,Molecular Medicine

Reference65 articles.

1. Carroll NM, Chiocca EA, Takahashi K, Tanabe KK . Enhancement of gene therapy specificity for diffuse colon carcinoma liver metastases with recombinant herpes simplex virus. Ann Surg 1996; 224: 323–329.

2. Pawlik TM, Nakamura H, Yoon SS, Mullen JT, Chandrasekhar S, Chiocca EA et al. Oncolysis of diffuse hepatocellular carcinoma by intravascular administration of a replication-competent, genetically engineered herpesvirus. Cancer Res 2000; 60: 2790–2795.

3. Yoon SS, Nakamura H, Carroll NM, Bode BP, Chiocca EA, Tanabe KK . An oncolytic herpes simplex virus type 1 selectively destroys diffuse liver metastases from colon carcinoma. FASEB J 2000; 14: 301–311.

4. Mullen JT, Donahue JM, Chandrasekhar S, Yoon SS, Liu W, Ellis LM et al. Oncolysis by viral replication and inhibition of angiogenesis by a replication-conditional herpes simplex virus that expresses mouse endostatin. Cancer 2004; 101: 869–877.

5. Nakamura H, Mullen JT, Chandrasekhar S, Pawlik TM, Yoon SS, Tanabe KK . Multimodality therapy with a replication-conditional herpes simplex virus 1 mutant that expresses yeast cytosine deaminase for intratumoral conversion of 5-fluorocytosine to 5-fluorouracil. Cancer Res 2001; 61: 5447–5452.

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