DNase II-dependent DNA digestion is required for DNA sensing by TLR9-Reference-Cited by-同舟云学术

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DNase II-dependent DNA digestion is required for DNA sensing by TLR9

Published:2015-01-20 Issue:1 Volume:6 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Chan Mei Po,Onji Masahiro,Fukui Ryutaro,Kawane Kohki,Shibata Takuma,Saitoh Shin-ichiroh,Ohto Umeharu,Shimizu Toshiyuki,Barber Glen N.,Miyake Kensuke

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms6853.pdf

Reference27 articles.

1. Atianand, M. K. & Fitzgerald, K. A. Molecular basis of DNA recognition in the immune system. J. Immunol. 190, 1911–1918 (2013).

2. Krieg, A. CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol. 20, 709–760 (2002).

3. Krug, A. et al. Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells. Eur. J. Immunol. 31, 2154–2163 (2001).

4. Vollmer, J. et al. Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities. Eur. J. Immunol. 34, 251–262 (2004).

5. Kerkmann, M. et al. Spontaneous formation of nucleic acid-based nanoparticles is responsible for high interferon-α induction by CpG-A in plasmacytoid dendritic cells. J. Biol. Chem. 280, 8086–8093 (2005).

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