Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspD-Reference-Cited by-同舟云学术

Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspD

Published:2016-11-18 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Price Kathryn E.,Armstrong Christopher M.,Imlay Leah S.,Hodge Dana M.,Pidathala C.,Roberts Natalie J.,Park Jooyoung,Mikati Marwa,Sharma Raman,Lawrenson Alexandre S.,Tolia Niraj H.,Berry Neil G.,O’Neill Paul M.,John Audrey R. Odom

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep36777.pdf

Reference58 articles.

1. Hale, I., O’Neill, P. M., Berry, N. G., Odom, A. & Sharma, R. The MEP pathway and the development of inhibitors as potential anti-infective agents. Medchemcomm 3, 418–433 (2012).

2. Odom, A. R. Five questions about non-mevalonate isoprenoid biosynthesis. Plos Pathog. 7, 1–4 (2011).

3. Rodriguez-Concepcion, M. The MEP pathway: a new target for the development of herbicides, antibiotics and antimalarial drugs. Curr. Pharm. Des. 10, 2391–2400 (2004).

4. Testa, C. A. & Brown, M. J. The methylerythritol phosphate pathway and its significance as a novel drug target. Curr. Pharm. Biotechnol. 4, 248–259 (2003).

5. Imlay, L. & Odom, A. R. Isoprenoid metabolism in apicomplexan parasites. Curr. Clin. Microbiol. reports 1, 37–50 (2014).

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