The right dose for every patient: a key step for precision medicine-Reference-Cited by-同舟云学术

The right dose for every patient: a key step for precision medicine

Published:2015-12-16 Issue:3 Volume:15 Page:145-146
ISSN:1474-1776
Container-title:Nature Reviews Drug Discovery
language:en
Short-container-title:Nat Rev Drug Discov

Author:

Peck Richard W.

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology,General Medicine

Link

http://www.nature.com/articles/nrd.2015.22.pdf

Reference5 articles.

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3. Wang, J. et al. Exposure–response relationship of T-DM1: insight into dose optimization for patients with HER2-positive metastatic breast cancer. Clin. Pharm. Ther. 95, 558–564 (2014).

4. Ohtsu, A. et al. Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: a randomized double-blind, placebo-controlled phase III study. J. Clin. Oncol. 29, 3968–3976 (2011).

5. Grahnen, A. & Karlsson, M. O. Concentration-controlled or effect-controlled clinical trials. Useful alternatives to conventional dose-controlled trials? Clin. Pharmacokinet. 40, 317–325 (2001).

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