Cellular uptake of exogenous calcineurin B is dependent on TLR4/MD2/CD14 complexes, and CnB is an endogenous ligand of TLR4
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep24346.pdf
Reference59 articles.
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2. Li, W. & Handschumacher, R. E. Identification of two calcineurin B-binding proteins: tubulin and heat shock protein 60. Biochim Biophys Acta. 1599, 72–81 (2002).
3. Saeki, M. et al. Calcineurin potentiates the activation of procaspase-3 by accelerating its proteolytic maturation. J Biol Chem. 282, 11786–11794 (2007).
4. Li, N., Zhang, Z., Zhang, W. & Wei Q. Calcineurin B subunit interacts with proteasome subunit alpha type 7 and represses hypoxia-inducible factor-1α activity via the proteasome pathway. Biochem Biophys Res Commun. 405, 468–472 (2011).
5. Jing, L. et al. Calcineurin subunit B activates dendritic cells and acts as a cancer vaccine adjuvant. Int Immunol. 23, 327–334 (2011).
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