Drug Insight: cancer cell immortality—telomerase as a target for novel cancer gene therapies
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,General Medicine
Link
http://www.nature.com/articles/ncponc0044.pdf
Reference48 articles.
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2. Keith WN et al. (2002) Telomerase-directed molecular therapeutics. Expert Rev Mol Med 2002: 1–25
3. Kim NW et al. (1994) Specific association of human telomerase activity with immortal cells and cancer. Science 266: 2011–2015
4. Masutomi K et al. (2000) Telomerase activity reconstituted in vitro with purified human telomerase reverse transcriptase and human telomerase RNA component. J Biol Chem 275: 22568–22573
5. Kim MM et al. (2001) A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation. Proc Natl Acad Sci USA 98: 7982–7987
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