A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway-Reference-Cited by-同舟云学术

A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway

Published:2014-12-16 Issue:4 Volume:93 Page:396-405
ISSN:0818-9641
Container-title:Immunology & Cell Biology
language:en
Short-container-title:Immunol Cell Biol

Author:

Helling Bianca¹,König Martin¹,Dälken Benjamin¹,Engling Andre¹,Krömer Wolfgang¹,Heim Katharina¹,Wallmeier Holger²,Haas Jürgen³,Wildemann Brigitte³,Fritz Brigitte³,Jonuleit Helmut⁴,Kubach Jan⁴,Dingermann Theodor⁵,Radeke Heinfried H⁶,Osterroth Frank¹,Uherek Christoph¹,Czeloth Niklas¹,Schüttrumpf Jörg¹

Affiliation:

1. Biotest AG Dreieich Germany

2. Condor Scientific Computing and Consulting Sulzbach Germany

3. Division of Molecular Neuroimmunology, Department of Neurology, University Hospital Heidelberg Heidelberg Germany

4. Department of Dermatology, Johannes Gutenberg University Mainz Germany

5. Institute of Pharmaceutical Biology, Goethe University Frankfurt Frankfurt Germany

6. Institute of Pharmacology and Toxicology, Clinic of the Goethe University Frankfurt Germany

Funder

Biotest AG

Publisher

Wiley

Subject

Cell Biology,Immunology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1038/icb.2014.102

Reference57 articles.

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2. Infectious Tolerance

3. "Infectious" Transplantation Tolerance

4. Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

5. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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