Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects-Reference-Cited by-同舟云学术

Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects

Published:2015-12 Issue:1 Volume:6 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Zhang Hongkai,Sturchler Emmanuel,Zhu Jiang,Nieto Ainhoa,Cistrone Philip A.,Xie Jia,He LinLing,Yea Kyungmoo,Jones Teresa,Turn Rachel,Di Stefano Peter S.,Griffin Patrick R.,Dawson Philip E.,McDonald Patricia H.,Lerner Richard A.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms9918.pdf

Reference55 articles.

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3. Willard, F. S. & Sloop, K. W. Physiology and emerging biochemistry of the glucagon-like peptide-1 receptor. Exp. Diabetes Res. 2012, 470851 (2012).

4. Thorens, B. Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1. Proc. Natl. Acad. Sci. USA 89, 8641–8645 (1992).

5. Montrose-Rafizadeh, C. et al. Pancreatic glucagon-like peptide-1 receptor couples to multiple G proteins and activates mitogen-activated protein kinase pathways in Chinese hamster ovary cells. Endocrinology 140, 1132–1140 (1999).

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