Conformational flexibility related to enzyme activity: evidence for a dynamic active-site gatekeeper function of Tyr215 in Aerococcus viridans lactate oxidase

Author:

Stoisser Thomas,Brunsteiner Michael,Wilson David K.,Nidetzky Bernd

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference54 articles.

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2. Palfey, B. A. & Massey, V. Flavin-dependent enzymes. Comprehensive Biological Catalysis: A Mechanistic Reference, Volume III Radical Reactions and Oxidation/Reduction (ed. Sinnott, M. ) 83–154 (Academic Press Limited, 1998).

3. Ghisla, S. & Massey, V. L-Lactate oxidase. In Chemistry and Biochemistry of Flavoproteins, Vol. II (ed. Müller, F. ) 243–289 (CRC Press, 1991).

4. Joosten, V. & van Berkel, W. J. H. Flavoenzymes. Curr. Opin. Chem. Biol. 11, 195–202 (2007).

5. Chayen, P., Fraaije, M. & Mattevi, A. The enigmatic reaction of flavins with oxygen. Trends Biochem. Sci. 37, 372–380 (2012).

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