Control of amino acid transport coordinates metabolic reprogramming in T-cell malignancy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
http://www.nature.com/articles/leu2017160.pdf
Reference48 articles.
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3. Macintyre AN, Finlay D, Preston G, Sinclair LV, Waugh CM, Tamas P et al. Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism. Immunity 2011; 34: 224–236.
4. Finlay DK, Rosenzweig E, Sinclair LV, Feijoo Carnero C, Hukelmann JL, Rolf J et al. PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells. J Exp Med 2012; 209: 2441–2453.
5. Akers LJ, Fang W, Levy AG, Franklin AR, Huang P, Zweidler-McKay PA . Targeting glycolysis in leukemia: a novel inhibitor 3-BrOP in combonation with rapamycin. Leukemia Res 2011; 35: 814–820.
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