Germline IKAROS mutation associated with primary immunodeficiency that progressed to T-cell acute lymphoblastic leukemia
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
https://www.nature.com/articles/leu201725.pdf
Reference15 articles.
1. Georgopoulos K, Bigby M, Wang JH, Molnar A, Wu P, Winandy S et al. The Ikaros gene is required for the development of all lymphoid lineages. Cell 1994; 79: 143–156.
2. Sun L, Liu A, Georgopoulos K . Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development. EMBO J 1996; 15: 5358–5369.
3. Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST . Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding. Genes Dev 2000; 14: 2146–2160.
4. Papathanasiou P, Perkins AC, Cobb BS, Ferrini R, Sridharan R, Hoyne GF et al. Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor. Immunity 2003; 19: 131–144.
5. Wang JH, Nichogiannopoulou A, Wu L, Sun L, Sharpe AH, Bigby M et al. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 1996; 5: 537–549.
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