Recombinant immunotoxins targeting B-cell maturation antigen are cytotoxic to myeloma cell lines and myeloma cells from patients
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
http://www.nature.com/articles/leu2017315.pdf
Reference15 articles.
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3. Wayne AS, Kreitman RJ, Findley HW, Lew G, Delbrok C, Steinberg SM et al. Anti-CD22 immunotoxin RFB4(dsFv)-PE38 (BL22) for CD22 positive hematologic malignancies of childhood: pre-clinical studies and Phase I clinical trial. Clin Cancer Res 2010; 16: 1894–1903.
4. Hassan R, Miller AC, Sharon E, Thomas A, Reynolds JC, Ling A et al. Major cancer regressions in mesothelioma after treatment with an anti-mesothelin immunotoxin and immune suppression. Sci Transl Med 2013; 5: 208ra147.
5. Kreitman RJ, Tallman MS, Robak T, Coutre S, Wilson WH, Stetler-Stevenson M et al. Phase I trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia. J Clin Oncol 2012; 30: 1822–1828.
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