Acyclic cucurbit[n]uril molecular containers enhance the solubility and bioactivity of poorly soluble pharmaceuticals-Reference-Cited by-同舟云学术

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Acyclic cucurbit[n]uril molecular containers enhance the solubility and bioactivity of poorly soluble pharmaceuticals

Published:2012-04-15 Issue:6 Volume:4 Page:503-510
ISSN:1755-4330
Container-title:Nature Chemistry
language:en
Short-container-title:Nature Chem

Author:

Ma Da,Hettiarachchi Gaya,Nguyen Duc,Zhang Ben,Wittenberg James B.,Zavalij Peter Y.,Briken Volker,Isaacs Lyle

Publisher

Springer Science and Business Media LLC

Subject

General Chemical Engineering,General Chemistry

Link

http://www.nature.com/articles/nchem.1326.pdf

Reference54 articles.

1. Hauss, D. J. Oral lipid-based formulations. Adv. Drug Deliv. Rev. 59, 667–676 (2007).

2. Lipinski, C. A. Drug-like properties and the causes of poor solubility and poor permeability. J. Pharmacol. Toxicol. Methods 44, 235–249 (2000).

3. Porter, C. J. H., Trevaskis, N. L. & Charman, W. N. Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs. Nature Rev. Drug Discov. 6, 231–248 (2007).

4. Leuner, C. & Dressman, J. Improving drug solubility for oral delivery using solid dispersions. Eur. J. Pharm. Biopharm. 50, 47–60 (2000).

5. Muller, R. H. & Keck, C. M. Challenges and solutions for the delivery of biotech drugs—a review of drug nanocrystal technology and lipid nanoparticles. J. Biotechnol. 113, 151–170 (2004).

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