Codon and mRNA Sequence Optimization of Microdystrophin Transgenes Improves Expression and Physiological Outcome in Dystrophic mdx Mice Following AAV2/8 Gene Transfer-Reference-Cited by-同舟云学术

Codon and mRNA Sequence Optimization of Microdystrophin Transgenes Improves Expression and Physiological Outcome in Dystrophic mdx Mice Following AAV2/8 Gene Transfer

Published:2008-11 Issue:11 Volume:16 Page:1825-1832
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Foster Helen,Sharp Paul S,Athanasopoulos Takis,Trollet Capucine,Graham Ian R,Foster Keith,Wells Dominic J,Dickson George

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference36 articles.

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3. Recombinant adeno-associated viral (rAAV) vectors as therapeutic tools for Duchenne muscular dystrophy (DMD);Athanasopoulos;Gene Ther,2004

4. Adeno-associated virus vector gene transfer and sarcolemmal expression of a 144 kDa micro-dystrophin effectively restores the dystrophin-associated protein complex and inhibits myofibre degeneration in nude/mdx mice;Fabb;Hum Mol Genet,2002

5. rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice;Gregorevic;Nat Med,2006

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