Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets
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Published:2018-04-16
Issue:5
Volume:50
Page:682-692
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Wedge David C.ORCID, , Gundem Gunes, Mitchell ThomasORCID, Woodcock Dan J., Martincorena Inigo, Ghori Mohammed, Zamora Jorge, Butler Adam, Whitaker Hayley, Kote-Jarai Zsofia, Alexandrov Ludmil B., Van Loo Peter, Massie Charlie E., Dentro Stefan, Warren Anne Y., Verrill Clare, Berney Dan M., Dennis Nening, Merson Sue, Hawkins Steve, Howat William, Lu Yong-Jie, Lambert Adam, Kay Jonathan, Kremeyer Barbara, Karaszi Katalin, Luxton Hayley, Camacho Niedzica, Marsden Luke, Edwards Sandra, Matthews Lucy, Bo Valeria, Leongamornlert Daniel, McLaren Stuart, Ng Anthony, Yu Yongwei, Zhang Hongwei, Dadaev Tokhir, Thomas Sarah, Easton Douglas F., Ahmed Mahbubl, Bancroft Elizabeth, Fisher Cyril, Livni Naomi, Nicol David, Tavaré Simon, Gill Pelvender, Greenman Christopher, Khoo Vincent, Van As Nicholas, Kumar Pardeep, Ogden Christopher, Cahill Declan, Thompson Alan, Mayer Erik, Rowe Edward, Dudderidge Tim, Gnanapragasam Vincent, Shah Nimish C., Raine Keiran, Jones David, Menzies Andrew, Stebbings Lucy, Teague Jon, Hazell Steven, Corbishley Cathy, de Bono Johann, Attard Gerhardt, Isaacs William, Visakorpi Tapio, Fraser Michael, Boutros Paul C., Bristow Robert G., Workman Paul, Sander Chris, Hamdy Freddie C., Futreal Andrew, McDermott Ultan, Al-Lazikani Bissan, Lynch Andrew G.ORCID, Bova G. StevenORCID, Foster Christopher S., Brewer Daniel S.ORCID, Neal David E.ORCID, Cooper Colin S., Eeles Rosalind A.ORCID,
Publisher
Springer Science and Business Media LLC
Reference83 articles.
1. Attard, G. et al. Prostate cancer. Lancet 387, 70–82 (2016). 2. Weischenfeldt, J. et al. Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer. Cancer Cell 23, 159–170 (2013). 3. Grasso, C. S. et al. The mutational landscape of lethal castration-resistant prostate cancer. Nature 487, 239–243 (2012). 4. Cancer Genome Atlas Research Network. The molecular taxonomy of primary prostate cancer. Cell 163, 1011–1025 (2015). 5. Barbieri, C. E. et al. Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Nat. Genet. 44, 685–689 (2012).
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