Chromothripsis followed by circular recombination drives oncogene amplification in human cancer-Reference-Cited by-同舟云学术

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Chromothripsis followed by circular recombination drives oncogene amplification in human cancer

Published:2021-11-15 Issue:12 Volume:53 Page:1673-1685
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Rosswog Carolina,Bartenhagen Christoph,Welte Anne^ORCID,Kahlert Yvonne,Hemstedt Nadine,Lorenz Witali,Cartolano Maria,Ackermann Sandra^ORCID,Perner Sven,Vogel Wenzel,Altmüller Janine,Nürnberg Peter,Hertwig Falk,Göhring Gudrun,Lilienweiss Esther,Stütz Adrian M.,Korbel Jan O.^ORCID,Thomas Roman K.,Peifer Martin^ORCID,Fischer Matthias^ORCID

Funder

Deutsche Forschungsgemeinschaft

Bundesministerium für Bildung und Forschung

Fördergesellschaft Kinderkrebs-Neuroblastom-Forschung e.V. Förderverein für krebskranke Kinder e.V. Köln

Else Kröner Fresenius Stiftung

Deutsche Krebshilfe

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

https://www.nature.com/articles/s41588-021-00951-7.pdf

Reference63 articles.

1. Storlazzi, C. T. et al. Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure. Genome Res 20, 1198–1206 (2010).

2. Biedler, J. L. & Spengler, B. A. Metaphase chromosome anomaly: association with drug resistance and cell-specific products. Science 191, 185–187 (1976).

3. Fan, Y. et al. Frequency of double minute chromosomes and combined cytogenetic abnormalities and their characteristics. J. Appl. Genet. 52, 53–59 (2011).

4. Koche, R. P. et al. Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma. Nat. Genet. 52, 29–34 (2020).

5. L’Abbate, A. et al. Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer. Nucleic Acids Res. 42, 9131–9145 (2014).

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