Improving the trans-ancestry portability of polygenic risk scores by prioritizing variants in predicted cell-type-specific regulatory elements-Reference-Cited by-同舟云学术

Improving the trans-ancestry portability of polygenic risk scores by prioritizing variants in predicted cell-type-specific regulatory elements

Published:2020-11-30 Issue:12 Volume:52 Page:1346-1354
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Amariuta Tiffany^ORCID,Ishigaki Kazuyoshi^ORCID,Sugishita Hiroki^ORCID,Ohta Tazro^ORCID,Koido Masaru^ORCID,Dey Kushal K.^ORCID,Matsuda Koichi^ORCID,Murakami Yoshinori^ORCID,Price Alkes L.^ORCID,Kawakami Eiryo^ORCID,Terao Chikashi^ORCID,Raychaudhuri Soumya^ORCID

Funder

U.S. Department of Health & Human Services | National Institutes of Health

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/s41588-020-00740-8.pdf

Reference64 articles.

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2. Vilhjálmsson, B. J. et al. Modeling linkage disequilibrium increases accuracy of polygenic risk scores. Am. J. Hum. Genet. 97, 576–592 (2015).

3. Finucane, H. K. et al. Partitioning heritability by functional annotation using genome-wide association summary statistics. Nat. Genet. 47, 1228–1235 (2015).