Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function
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Published:2022-01
Issue:1
Volume:54
Page:18-29
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Hawe Johann S.ORCID, Wilson RoryORCID, Schmid Katharina T.ORCID, Zhou Li, Lakshmanan Lakshmi NarayananORCID, Lehne Benjamin C., Kühnel Brigitte, Scott William R.ORCID, Wielscher Matthias, Yew Yik Weng, Baumbach Clemens, Lee Dominic P., Marouli EiriniORCID, Bernard Manon, Pfeiffer Liliane, Matías-García Pamela R., Autio Matias I.ORCID, Bourgeois StephaneORCID, Herder Christian, Karhunen VilleORCID, Meitinger Thomas, Prokisch HolgerORCID, Rathmann Wolfgang, Roden Michael, Sebert SylvainORCID, Shin JeanORCID, Strauch Konstantin, Zhang WeihuaORCID, Tan Wilson L. W., Hauck Stefanie M.ORCID, Merl-Pham JulianeORCID, Grallert Harald, Barbosa Eudes G. V., Ahmadi Kourosh R., Ainali Chrysanthi, Barrett Amy, Bataille Veronique, Bell Jordana T., Buil Alfonso, Dermitzakis Emmanouil T., Dimas Antigone S., Durbin Richard, Glass Daniel, Grundberg Elin, Hassanali Neelam, Hedman Åsa K., Ingle Catherine, Knowles David, Krestyaninova Maria, Lindgren Cecilia M., Lowe Christopher E., McCarthy Mark I., Meduri Eshwar, di Meglio Paola, Min Josine L., Montgomery Stephen B., Nestle Frank O., Nica Alexandra C., Nisbet James, O’Rahilly Stephen, Parts Leopold, Potter Simon, Sandling Johanna, Sekowska Magdalena, Shin So-Youn, Small Kerrin S., Soranzo Nicole, Spector Tim D., Surdulescu Gabriela, Travers Mary E., Tsaprouni Loukia, Tsoka Sophia, Wilk Alicja, Yang Tsun-Po, Zondervan Krina T., Illig Thomas, Peters AnnetteORCID, Paus TomasORCID, Pausova ZdenkaORCID, Deloukas PanosORCID, Foo Roger S. Y.ORCID, Jarvelin Marjo-RiittaORCID, Kooner Jaspal S.ORCID, Loh MarieORCID, Heinig MatthiasORCID, Gieger ChristianORCID, Waldenberger MelanieORCID, Chambers John C.ORCID,
Funder
DH | National Institute for Health Research MOH | National Medical Research Council
Publisher
Springer Science and Business Media LLC
Reference84 articles.
1. Bird, A. Perceptions of epigenetics. Nature 447, 396–398 (2007). 2. Schubeler, D. Function and information content of DNA methylation. Nature 517, 321–326 (2015). 3. Parry, A., Rulands, S. & Reik, W. Active turnover of DNA methylation during cell fate decisions. Nat. Rev. Genet. 22, 59–66 (2021). 4. Jaenisch, R. & Bird, A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 33, 245–254 (2003). 5. Chambers, J. C. et al. Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case–control study. Lancet Diabetes Endocrinol. 3, 526–534 (2015).
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