Comprehensive characterization of protein–protein interactions perturbed by disease mutations-Reference-Cited by-同舟云学术

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Comprehensive characterization of protein–protein interactions perturbed by disease mutations

Published:2021-02-08 Issue:3 Volume:53 Page:342-353
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Cheng Feixiong^ORCID,Zhao Junfei,Wang Yang,Lu Weiqiang^ORCID,Liu Zehui,Zhou Yadi,Martin William R.^ORCID,Wang Ruisheng,Huang Jin,Hao Tong^ORCID,Yue Hong^ORCID,Ma Jing,Hou Yuan,Castrillon Jessica A.,Fang Jiansong,Lathia Justin D.,Keri Ruth A.,Lightstone Felice C.^ORCID,Antman Elliott Marshall^ORCID,Rabadan Raul^ORCID,Hill David E.^ORCID,Eng Charis^ORCID,Vidal Marc,Loscalzo Joseph^ORCID

Funder

American Heart Association

Foundation for the National Institutes of Health

VeloSano Pilot Program (Cleveland Clinic Taussig Cancer Institute

the Sondra J. and Stephen R. Hardis Endowed Chair in Cancer Genomic Medicine at the Cleveland Clinic, and an ACS Clinical Research Professor.

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/s41588-020-00774-y.pdf

Reference64 articles.

1. Bailey, M. H. et al. Comprehensive characterization of cancer driver genes and mutations. Cell 173, 371–385 (2018).

2. Cheng, F., Liang, H., Butte, A. J., Eng, C. & Nussinov, R. Personal mutanomes meet modern oncology drug discovery and precision health. Pharmacol. Rev. 71, 1–19 (2019).

3. Sahni, N. et al. Widespread macromolecular interaction perturbations in human genetic disorders. Cell 161, 647–660 (2015).

4. Ng, P. K. et al. Systematic functional annotation of somatic mutations in cancer. Cancer Cell 33, 450–462 (2018).

5. Chen, S. et al. An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders. Nat. Genet. 50, 1032–1040 (2018).

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