Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases
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Published:2020-06-08
Issue:7
Volume:52
Page:669-679
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Ishigaki KazuyoshiORCID, Akiyama Masato, Kanai MasahiroORCID, Takahashi AtsushiORCID, Kawakami Eiryo, Sugishita HirokiORCID, Sakaue SaoriORCID, Matoba NanaORCID, Low Siew-Kee, Okada Yukinori, Terao ChikashiORCID, Amariuta TiffanyORCID, Gazal StevenORCID, Kochi Yuta, Horikoshi Momoko, Suzuki KenORCID, Ito Kaoru, Koyama Satoshi, Ozaki Kouichi, Niida Shumpei, Sakata Yasushi, Sakata Yasuhiko, Kohno Takashi, Shiraishi Kouya, Momozawa Yukihide, Hirata MakotoORCID, Matsuda KoichiORCID, Ikeda MasashiORCID, Iwata NakaoORCID, Ikegawa ShiroORCID, Kou Ikuyo, Tanaka Toshihiro, Nakagawa Hidewaki, Suzuki Akari, Hirota Tomomitsu, Tamari MayumiORCID, Chayama Kazuaki, Miki Daiki, Mori Masaki, Nagayama SatoshiORCID, Daigo Yataro, Miki Yoshio, Katagiri Toyomasa, Ogawa Osamu, Obara Wataru, Ito HidemiORCID, Yoshida Teruhiko, Imoto Issei, Takahashi Takashi, Tanikawa Chizu, Suzuki Takao, Sinozaki Nobuaki, Minami Shiro, Yamaguchi HirokiORCID, Asai Satoshi, Takahashi Yasuo, Yamaji Ken, Takahashi Kazuhisa, Fujioka Tomoaki, Takata RyoORCID, Yanai Hideki, Masumoto Akihide, Koretsune Yukihiro, Kutsumi Hiromu, Higashiyama Masahiko, Murayama Shigeo, Minegishi Naoko, Suzuki Kichiya, Tanno Kozo, Shimizu AtsushiORCID, Yamaji Taiki, Iwasaki Motoki, Sawada NorieORCID, Uemura Hirokazu, Tanaka KeitaroORCID, Naito Mariko, Sasaki MakotoORCID, Wakai Kenji, Tsugane ShoichiroORCID, Yamamoto Masayuki, Yamamoto Kazuhiko, Murakami YoshinoriORCID, Nakamura Yusuke, Raychaudhuri SoumyaORCID, Inazawa JohjiORCID, Yamauchi ToshimasaORCID, Kadowaki TakashiORCID, Kubo MichiakiORCID, Kamatani YoichiroORCID
Funder
Japan Agency for Medical Research and Development National Cancer Center Research and Development Fund
Publisher
Springer Science and Business Media LLC
Reference61 articles.
1. Martin, A. R. et al. Clinical use of current polygenic risk scores may exacerbate health disparities. Nat. Genet. 51, 584–591 (2019). 2. Popejoy, A. B. & Fullerton, S. M. Genomics is failing on diversity. Nature 538, 161–164 (2016). 3. Morales, J. et al. A standardized framework for representation of ancestry data in genomics studies, with application to the NHGRI-EBI GWAS Catalog. Genome Biol. 19, 21 (2018). 4. Diversity matters. Nat. Rev. Genet. 20, 495 (2019). 5. Sirugo, G., Williams, S. M. & Tishkoff, S. A. The missing diversity in human genetic studies. Cell 177, 26–31 (2019).
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