cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing
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Published:2020-11-23
Issue:12
Volume:52
Page:1364-1372
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Uggenti Carolina, Lepelley AliceORCID, Depp Marine, Badrock Andrew P., Rodero Mathieu P., El-Daher Marie-Thérèse, Rice Gillian I.ORCID, Dhir Somdutta, Wheeler Ann P., Dhir Ashish, Albawardi Waad, Frémond Marie-Louise, Seabra LuisORCID, Doig Jennifer, Blair Natalie, Martin-Niclos Maria José, Della Mina ErikaORCID, Rubio-Roldán AlejandroORCID, García-Pérez Jose L.ORCID, Sproul DuncanORCID, Rehwinkel Jan, Hertzog JonnyORCID, Boland-Auge AnneORCID, Olaso Robert, Deleuze Jean-FrançoisORCID, Baruteau JulienORCID, Brochard Karine, Buckley Jonathan, Cavallera Vanessa, Cereda Cristina, De Waele Liesbeth M. H., Dobbie Angus, Doummar Diane, Elmslie Frances, Koch-Hogrebe Margarete, Kumar Ram, Lamb Kate, Livingston John H.ORCID, Majumdar Anirban, Lorenço Charles Marques, Orcesi SimonaORCID, Peudenier Sylviane, Rostasy Kevin, Salmon Caroline A., Scott ChristiaanORCID, Tonduti DavideORCID, Touati Guy, Valente Marialuisa, van der Linden Hélio, Van Esch Hilde, Vermelle Marie, Webb KateORCID, Jackson Andrew P., Reijns Martin A. M.ORCID, Gilbert NickORCID, Crow Yanick J.ORCID
Publisher
Springer Science and Business Media LLC
Reference48 articles.
1. Roers, A., Hiller, B. & Hornung, V. Recognition of endogenous nucleic acids by the innate immune system. Immunity 44, 739–754 (2016). 2. Uggenti, C., Lepelley, A. & Crow, Y. J. Self-awareness: nucleic acid-driven inflammation and the type I interferonopathies. Annu. Rev. Immunol. 37, 247–267 (2019). 3. Bartsch, K. et al. Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy. Hum. Mol. Genet. 26, 3960–3972 (2017). 4. Harding, S. M. et al. Mitotic progression following DNA damage enables pattern recognition within micronuclei. Nature 548, 466–470 (2017). 5. Mackenzie, K. J. et al. cGAS surveillance of micronuclei links genome instability to innate immunity. Nature 548, 461–465 (2017).
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