Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits-Reference-Cited by-同舟云学术

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Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits

Published:2019-09-30 Issue:10 Volume:51 Page:1506-1517
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Benaglio Paola,D’Antonio-Chronowska Agnieszka,Ma Wubin,Yang Feng,Young Greenwald William W.,Donovan Margaret K. R.,DeBoever Christopher,Li He^ORCID,Drees Frauke,Singhal Sanghamitra,Matsui Hiroko,van Setten Jessica^ORCID,Sotoodehnia Nona,Gaulton Kyle J.,Smith Erin N.,D’Antonio Matteo^ORCID,Rosenfeld Michael G.^ORCID,Frazer Kelly A.^ORCID

Funder

California Institute for Regenerative Medicine

National Science Foundation

U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences

Howard Hughes Medical Institute

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/s41588-019-0499-3.pdf

Reference85 articles.

1. MacArthur, J. et al. The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog). Nucleic Acids Res. 45, D896–D901 (2017).

2. Gallagher, M. D. & Chen-Plotkin, A. S. The post-GWAS era: from association to function. Am. J. Hum. Genet. 102, 717–730 (2018).

3. Van den Boogaard, M. et al. A common genetic variant within SCN10A modulates cardiac SCN5A expression. J. Clin. Invest. 124, 1844–1852 (2014).

4. Wang, X. et al. Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures. eLife 5, e10557 (2016).

5. Deplancke, B., Alpern, D. & Gardeux, V. The genetics of transcription factor DNA binding variation. Cell 166, 538–554 (2016).

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