Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition-Reference-Cited by-同舟云学术

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

Published:2018-04 Issue:4 Volume:50 Page:572-580
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Small Kerrin S.^ORCID,Todorčević Marijana,Civelek Mete^ORCID,El-Sayed Moustafa Julia S.,Wang Xiao,Simon Michelle M.,Fernandez-Tajes Juan,Mahajan Anubha^ORCID,Horikoshi Momoko,Hugill Alison,Glastonbury Craig A.,Quaye Lydia,Neville Matt J.^ORCID,Sethi Siddharth,Yon Marianne,Pan Calvin,Che Nam,Viñuela Ana^ORCID,Tsai Pei-Chien,Nag Abhishek,Buil Alfonso^ORCID,Thorleifsson Gudmar,Raghavan Avanthi,Ding Qiurong,Morris Andrew P.,Bell Jordana T.,Thorsteinsdottir Unnur,Stefansson Kari,Laakso Markku,Dahlman Ingrid,Arner Peter,Gloyn Anna L.^ORCID,Musunuru Kiran,Lusis Aldons J.,Cox Roger D.^ORCID,Karpe Fredrik,McCarthy Mark I.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/s41588-018-0088-x.pdf

Reference62 articles.

1. Kong, A. et al. Parental origin of sequence variants associated with complex diseases. Nature 462, 868–874 (2009).

2. Voight, B. F. et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat. Genet. 42, 579–589 (2010).

3. Small, K. S. et al. Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes. Nat. Genet. 43, 561–564 (2011).

4. Dang, D. T., Pevsner, J. & Yang, V. W. The biology of the mammalian Kruppel-like family of transcription factors. Int. J. Biochem. Cell Biol. 32, 1103–1121 (2000).

5. Wu, Z. & Wang, S. Role of kruppel-like transcription factors in adipogenesis. Dev. Biol. 373, 235–243 (2013).

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