Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics-Reference-Cited by-同舟云学术

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Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics

Published:2020-05-25 Issue:7 Volume:52 Page:740-747
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Morrison Jean^ORCID,Knoblauch Nicholas,Marcus Joseph H.^ORCID,Stephens Matthew^ORCID,He Xin^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health

March of Dimes Foundation

U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/s41588-020-0631-4.pdf

Reference31 articles.

1. Smith, G. D. & Ebrahim, S. ‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease? Int. J. Epidemiol. 32, 1–22 (2003).

2. Smith, G. D. & Hemani, G. Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Hum. Mol. Genet. 23, 89–98 (2014).

3. Boef, A. G. C., Dekkers, O. M. & Le Cessie, S. Mendelian randomization studies: a review of the approaches used and the quality of reporting. Int. J. Epidemiol. 44, 496–511 (2015).

4. Zheng, J. et al. Recent developments in Mendelian randomization studies. Curr. Epidemiol. Rep. 4, 330–345 (2017).

5. Burgess, S., Dudbridge, F. & Thompson, S. G. Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods. Stat. Med. 35, 1880–1906 (2016).

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