Global impact of unproductive splicing on human gene expression-Reference-Cited by-同舟云学术

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Global impact of unproductive splicing on human gene expression

Published:2024-09 Issue:9 Volume:56 Page:1851-1861
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Fair Benjamin^ORCID,Buen Abad Najar Carlos F.^ORCID,Zhao Junxing,Lozano Stephanie^ORCID,Reilly Austin,Mossian Gabriela,Staley Jonathan P.^ORCID,Wang Jingxin,Li Yang I.^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences

U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute

W. M. Keck Foundation

GREGoR Consortium

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41588-024-01872-x.pdf

Reference86 articles.

1. Barbosa-Morais, N. L. et al. The evolutionary landscape of alternative splicing in vertebrate species. Science 338, 1587–1593 (2012).

2. Merkin, J., Russell, C., Chen, P. & Burge, C. B. Evolutionary dynamics of gene and isoform regulation in mammalian tissues. Science 338, 1593–1599 (2012).

3. Mudge, J. M. et al. The origins, evolution, and functional potential of alternative splicing in vertebrates. Mol. Biol. Evol. 28, 2949–2959 (2011).

4. Bénitère, F., Necsulea, A. & Duret, L. Random genetic drift sets an upper limit on mRNA splicing accuracy in metazoans. Evol. Biol. https://doi.org/10.1101/2022.12.09.519597 (2022).

5. Saudemont, B. et al. The fitness cost of mis-splicing is the main determinant of alternative splicing patterns. Genome Biol. 18, 208 (2017).

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