Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities
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Published:2022-05
Issue:5
Volume:54
Page:649-659
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Choudhury AbrarORCID, Magill Stephen T.ORCID, Eaton Charlotte D., Prager Briana C., Chen William C., Cady Martha A., Seo Kyounghee, Lucas Calixto-Hope G.ORCID, Casey-Clyde Tim J.ORCID, Vasudevan Harish N., Liu S. JohnORCID, Villanueva-Meyer Javier E., Lam Tai-Chung, Pu Jenny Kan-Suen, Li Lai-FungORCID, Leung Gilberto Ka-Kit, Swaney Danielle L.ORCID, Zhang Michael Y., Chan Jason W., Qiu ZhixinORCID, Martin Michael V., Susko Matthew S., Braunstein Steve E., Bush Nancy Ann Oberheim, Schulte Jessica D., Butowski Nicholas, Sneed Penny K., Berger Mitchel S., Krogan Nevan J.ORCID, Perry ArieORCID, Phillips Joanna J.ORCID, Solomon David A.ORCID, Costello Joseph F.ORCID, McDermott Michael W., Rich Jeremy N.ORCID, Raleigh David R.ORCID
Funder
U.S. Department of Health & Human Services | National Institutes of Health
Publisher
Springer Science and Business Media LLC
Reference89 articles.
1. Bi, W. L. et al. Genomic landscape of intracranial meningiomas. J. Neurosurg. 125, 525–535 (2016). 2. Vasudevan, H. N. et al. Comprehensive molecular profiling identifies FOXM1 as a key transcription factor for meningioma proliferation. Cell Rep. 22, 3672–3683 (2018). 3. Zhou, W., Triche, T. J., Laird, P. W. & Shen, H. SeSAMe: reducing artifactual detection of DNA methylation by Infinium BeadChips in genomic deletions. Nucleic Acids Res. 46, e123–e123 (2018). 4. Sahm, F. et al. DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis. Lancet Oncol. 18, 682–694 (2017). 5. Olar, A. et al. Global epigenetic profiling identifies methylation subgroups associated with recurrence-free survival in meningioma. Acta Neuropathol. 133, 431–444 (2017).
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