4′-O-substitutions determine selectivity of aminoglycoside antibiotics

Author:

Perez-Fernandez Déborah,Shcherbakov Dmitri,Matt Tanja,Leong Ng Chyan,Kudyba Iwona,Duscha Stefan,Boukari Heithem,Patak Rashmi,Dubbaka Srinivas Reddy,Lang Kathrin,Meyer Martin,Akbergenov Rashid,Freihofer Pietro,Vaddi Swapna,Thommes Pia,Ramakrishnan V.,Vasella Andrea,Böttger Erik C.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Reference49 articles.

1. Poehlsgaard, J. & Douthwaite, S. The bacterial ribosome as a target for antibiotics. Nat. Rev. Microbiol. 3, 870–881 (2005).

2. Wilson, D. N. The A-Z of bacterial translation inhibitors. Crit. Rev. Biochem. Mol. Biol. 44, 393–433 (2009).

3. World Health Organisation, Report of the second WHO Expert Meeting, Copenhagen, Denmark (2007) Critically important antimicrobials for human health, http://www.who.int/foodborne_disease/resistance/antimicrobials_human.pdf (WHO, Geneva, Switzerland).

4. Chambers, H. F. Chemotherapy of microbial diseases. In: Goodmann & Gilman’sThe Pharmaceutical Basis of Therapeutics 10th edn Eds Hardman J. G., Limbird L. E. 1103–1121The McGraw-Hill Companies (1996).

5. Forge, A. & Schacht, J. Aminoglycoside antibiotics. Audiol. Neurootol. 5, 3–22 (2000).

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